Endometriosis is a gynecological condition in which cells from the lining of the uterus (endometrium) appear and flourish outside the uterine cavity, most commonly on the membrane which lines the abdominal cavity, the peritoneum. The uterine cavity is lined with endometrial cells, which are under the influence of female hormones. Endometrial cells in areas outside the uterus are also influenced by hormonal changes and respond in a way that is similar to the cells found inside the uterus. Symptoms of endometriosis are pain and infertility.
Fibroids are non-cancerous (benign) tumors that grow from the muscle layers of the uterus (womb). They are also known as uterine fibroids, myomas, or fibromyomas. The singular of uterine fibroids is Uterine Fibroma. Fibroids are growths of smooth muscle and fibrous tissue. Fibroids can vary in size, from that of a bean to as large as a melon.
Fibroids affect at least 20% of all women at sometime during their life. Women aged between 30 and 50 are the most likely to develop fibroids. Overweight and obese women are at significantly higher risk of developing fibroids, compared to women of normal weight.
Lupron Depot (leuprolide acetate for depot suspension), a GnRH agonist, is a hormonal agent that significantly reduces estrogen levels. The medication works in two distinct phases. Phase one stimulates the ovaries causing them to produce more estradiol, the most potent of the three estrogens produced by women. In phase two, the messenger hormones that tell the ovaries to produce estrogen decline dramatically. The resulting drop in estrogen causes women to experience menopause-like side effects.